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The 9 Best Arthritis Creams of 2021

Final Verdict

When considering which topical medications might be best for you, it is important to consider the active ingredients in the product. Topicals can contain a variety of different active ingredients that vary from product to product. If you find that one product isn’t working for you, then it might be best to try one with a different active ingredient. 

For a natural pain-reliever, the Naturopathic Arnica Gel (view at Amazon) is hard to beat. It’s the preferred product arthritis sufferers return to again and again for muscle aches, swelling, and joints. And for convenience, you can’t go wrong with the Biofreeze Professional Relief Aerosol Colorless (view at Amazon) for long-lasting relief and mess-free application. Ultimately, it comes down to personal preference. Dr. Rosian says, “I think you need to try and see what works best for you.”

What to Look for in an Arthritis Cream

Active Ingredients

There are several effective ingredients that relieve pain, inflammation, and stiffness in joints caused by arthritis. Topical anesthetics, like lidocaine, create a surface-level numbing effect wherever they're applied. Natural ingredients like menthol, camphor, eucalyptus oil, and cinnamon oil create hot and cold sensations on contact and have anti-inflammatory properties to soothe sore joints. The added sensation they create helps dull pain.

“Most agents have cooling agents like menthol or capsaicin,” says Alejandra Rodriguez-Paez, M.D., a rheumatologist with the Illinois Joint & Bone Institute.. This agent depletes the nerve cells in the area of a chemical that’s important for sending pain signals to the brain. “They cause the skin to feel cool and then warm and they distract the nerve endings from the pain sensation thus relieving pain,” Dr. Paez adds. “Usually the effect is short lived, it goes away if not used frequently.” 

Side Effects

Oral medications to relieve arthritis symptoms can sometimes cause gastrointestinal problems, stomach ulcers, and kidney dysfunction. Topical medications, on the other hand, minimize some of those side effects seen in their oral counterparts. “I believe the side effect profile in general is safe, and patients may have a benefit, which would lead them to avoid using other oral agents that have potential for more side effects,” Dr. Paez says. 

But that doesn’t mean these topical agents are for everyone. Because the product is applied directly to the skin, it could cause irritation for people with skin conditions or similar sensitivities. “Patients with different skin conditions, history of eczema or sensitive skin may want to use a small amount first to see if it causes problems,” says Dr. Paez. If you experience a severe skin reaction to the product, it is best to stop use and speak to your doctor about the ingredients that potentially caused the reaction. 


While rollers and patches may seem convenient, doctors say you may be missing out on one major benefit of using an arthritis cream: the massage. “The act of actually putting on some of these rubs may be, at least in part, why they’re helpful,” says Dr. Rosian. “Massaging the cream or gel in and moving around the joints helps with blood flow and modulating the pain around the area.”

Frequently Asked Questions

  • Arthritis creams—also known as topicals or ointments—work on the area they are applied to either reduce pain, reduce inflammation, or both, according to Rachel Frank, M.D., an orthopedic surgeon at UCHealth and director of the Joint Preservation Program at the University of Colorado School of Medicine.

    “[Some] arthritis creams are formulated with salicylates, which can reduce inflammation to the joints when applied topically and lessen pain,” Niket Sonpal, M.D., an internist practicing in New York City tells Verywell Health. “Some creams use ingredients known as ‘counterirritants,’ which actually cause mild irritation or inflammation of the skin to distract the patient from their arthritis’ pain. Menthol, or mint oil, is a common counterirritant often used in arthritis creams.”

  • Always read the product's label to guarantee you're using the appropriate dose.

    "Many of the products are best used when applied multiple times per day, and so to get the most benefit, patients must be willing to follow the instructions and use appropriately," says Rachel Frank, M.D., an orthopedic surgeon at UCHealth and director of the Joint Preservation Program at the University of Colorado School of Medicine. "As always, talk to your doctor first before starting.”

  • Any medication, including arthritis creams or gels, should be discussed with your primary care provider before using—especially if you’re pregnant or breastfeeding,” according to Frank. “While topical agents may be of lower risk than oral agents, there is still a risk of systemic absorption, and may be contraindicated while pregnant or breastfeeding—particularly anything containing an NSAID,” she explains.

    According to Sonpal, topical arthritis creams are usually safe for use while pregnant or breastfeeding. “This is because when treatment, like a cream, is applied topically, the skin absorbs very little of the medication,” he explains. “It is unlikely that a harmful amount of medication from the cream will move through your bloodstream into your uterus or your breastmilk, if you are breastfeeding. If you are unsure of whether or not it is safe to use your specific arthritis cream while pregnant or breastfeeding, consult your doctor for a medical opinion.”

What the Experts Say

“It is advised to look at the ingredients list of a cream to see if it is formulated with topical anesthetics which can help numb the affected area and lessen pain. If you are someone with extremely sensitive skin, it may be beneficial to look for an arthritis cream that caters to sensitive skin and is less irritative. The side effects list can show you what symptoms you may be subjected to after using the cream. If you already suffer from any of those conditions, it is advised to consult your doctor prior to use.” —Niket Sonpal, M.D., an internist practicing in New York City

Why Trust Verywell Health?

As a seasoned health writer, Jennifer Nied understands how vital quality product recommendations are for treating symptoms safely and effectively at home. For over 10 years, she has reviewed products, interviewed experts, scrutinized ingredients, and pored over research studies and claims, to help readers like you understand what works for your specific conditions. Every product in this piece was selected taking into account recommendations from doctors, published research, and real customer reviews.

Additional reporting to this story by Danielle Zoellner and Elizabeth Yuko

As a seasoned health writer, Danielle Zoellner knows the importance of finding just the right product to fit your medical needs. Throughout her career, Danielle has interviewed a variety of experts in the medical and health fields while reviewing dozens of products. Her experience and knowledge in the field work together to help readers like yourself find the best products for your daily life.

As a seasoned health writer and editor—and someone with rheumatoid arthritis—Elizabeth Yuko understands how much of a difference finding the right product makes for those with arthritis. She’s always on the lookout for new (and research-backed) products, techniques, and services that can help people cope with their health challenges.

Arthritis Pain Relief that is Natural Cheap and WORKS Amazingly Well
Koru FX (Relief Fx)
I was knocked off my motorbike in mid March this year by and errant motorist and have gone through hospitalization, convalescence, physio etc but I have been left with swollen and painful ankle. Using Koru FX I have been able to bring the swelling down and ease the pain in the ankle and I am again able to ride my new motorcycle ..... the last one did not survive the accident.
Koru FX (Relief Fx)
I love this rub. It really did help me with my arthritis. Which I got on my back knee and shoulders. Give me a lot of relief. Thankfully to koru
Koru FX (Relief Fx)
I use this for all sorts of muscle pain. My 94 year Mum says its the only thing that helps her worn out shoulder and my husband uses it when he gets cramp and it relieves it immediately. Great stuff!
Koru FX (Relief Fx)
I have been using Koru fx for quite some time now after finding it online. After being a top sportsman years ago and keeping myself in reasonable shape my knees were holding me back from walking etc! Now after using Koru fx plus joint fx I am able to do all those exercises again!!! People & friends I have told keep thanking me and say how good it is . Regards. Peter R
Koru FX (Relief Fx)
I broke my thumb last year and although it has healed, I was still getting a lot of ongoing pain. KORU FX is great at relieving the pain. Nothing else works as good.
Koru FX (Relief Fx)
Its great pain relief ! I play a lot of badminton and my knee gives me a bit of a challenge. Relief Fx is so good half way through my game. Its my second lot I've ordered. Highly recommended it plus it smells great.
Koru FX (Relief Fx)
We are all good at present with plenty of RELIEF Fx to use daily. Wonderful product which my husband & I use every day. As my husband is waiting on a knee replacement it certainly helps with the pain at present' For myself it just keeps me going every day.
Koru FX (Relief Fx)
I love the Relief FX. It really helps my poor knee and the rest of my aches and pains. I fractured my back about 5 years ago and it helps to rub it on after my shower each day. I have also started taking Koru Protect and Gut Restore and have noticed a definite improvement of both my mood and my gut problem brought on by my gluten allergy. I also have a lot more energy which is great when I go for my daily walk!
Koru FX (Relief Fx)
We brought both cream and tablets! Also got a free mothers day free marine collagen. So amazing! The cream is very soothing and my 87 year old father has started the tablets and says the aching has stopped.
Koru FX Cream
I first noticed this product on Face Book when Peter Williams was talking about it so as I was suffering from Arthritis I thought it would be worth a try? I generally try to apply the Koru FX twice a day and it has helped me no end. I am able to walk with no pain in my right knee a real blessing!!
Koru FX (Relief Fx)
This time I've used koru fx joint nd muscle support for my headache and my slight earache. It's velvet like texture feels good against them. I usually use it for my fibromyalgia but actually I use it also as a quick pick me up rub on everything. Just adore this product.
Koru FX Cream
I have found koru fx instant relief l damaged a muscle on my upper arm lam receiving treatment from a physio l find the cream very helpful after being in the garden
Koru FX Cream
I suffer from arthritis in my hands and fingers and have tried many different creams, nothing has worked as well and as fast as this. I'm so happy to have found this
Koru FX Cream
Have been using FX for over a year now. It is wonderful for the arthritis in my knees and hands. I have pancreatic cancer and have to be very careful what products I use. Thank you for your wonderful products.
Koru FX Cream
Thank you your product Koru Nutrition relief Fx. I’m loving that it is made of natural ingredients. Definitely helps my back pain and joint pain in my knee. Also my son used it after a hard days work and had a sore back, so I gave him one of these to try out. He mentioned how fast it worked for him, he was impressed with your product!
Koru FX Cream
Love this product use it on my sore knee most mornings and it gets me through the day, Hubby had a sore arm he is a double amputee so he needs to be pain free as his arms are what he uses to transfer he has been using this as well and finds it helps to set him up for the day. He is 77 so it’s great it helps. Love when you have great specials I have a few extra on hand all the time, thanks for the great specials it really helps as we are both on pensions. Thankyou
Koru FX Cream
Don is never without his Relief Fx..keeps it beside him every day.I have pleasure in recommending the product to others as I know it really works Good on you Koru Nutition you are the best.👍
Koru FX Cream
I found your products excellent, the natural ingredients and consistency smooth and healing. The after effects were effective giving relief enabling the joint to move more freely without being conscious of so much pain. The service and delivery was quick and efficient, after ordering online it was in my post box within hours. The applicator works well and the pump action user friendly. Overall a great product!
Koru FX Cream
I have been using KORU FX cream for the past two months or so and find it very effective for a "dodgy" knee I have! It certainly has helped reduce joint pain on my daily walks. I am now taking KORU joint FX tablets to assist even more ! I call it good old South Island ingenuity. Thank you Micahel Lee, Wellington.
Koru FX Cream
I find Koru Fx excellent. It has helped the pain extremely well in my right leg, left knee & back so it is used sometimes 2-3 times per day. What more can I say about this product.
Koru FX Cream
I use RELIEF Fx on my back every morning it allows me to do the thing l enjoy like walking my dog and my neighbours every morning also spending time with a friend visiting all the old gold mining sites in central otago.
Relief Fx
After reading many reviews of relief fx I decided I had to try this product for my aching knee and occasionally aching finger joints. On the fingers, the reaction is almost immediate. Quite unbelievable. The knee has taken a little longer but it definitely helps and I find it useful to rub some on before any exercise ( walking and biking). The website is very user friendly. Excellent customer service and quick delivery. The Xmas special offers have been great.
Koru FX Cream
Hi Molly thankyou for your great product Koru fx. It gets me through the day and gets me through the night reducing my pain considerably. I'm able to enjoy my life with my daughters and granddaughter. Your web site is easy to follow and your delivery time is wonderful, I also enjoy your friendly emails. So please keep up the good work of supplying your marvellous products. Thankyou so much Ana
Koru FX Cream
This product has helped me with the pain and inflammation in both my knees due to osteoarthritis. I'm on my feet 5 days a week with work so have found it supports my day and makes it bearable. 😍
Koru FX Cream
I have previously travelled overseas and taken Koru Nutrition cream in my luggage. The help and benefits when applied gives relief from pain and gives the body a “get up and go ‘ feeling. Long may it last. Thank you 🙏
Koru FX Cream
When I came to Waipu and wanted to walk along the beach!!!~ But sadly my knees wouldn't do it!! I had to take a Voltaren Tablet 1/2 an hour before the walk. After 2 months I got fed up with pills so I found Koru and I have to say, that after 3 weeks I never needed to take a pill again, the Relief Fx is marvellous, and to this day nearly 3 years later I have never had a pain in either knees , and I am still ordering it and the Joint Fx, not just for me, but for friends too. So thank you very v...
Koru FX Cream
I saw the doctor 3 times and all they can do supply me with pain killers they work for a while but was satisfied with that a friend of my off the coast sent me an paper article from the local paper saying about relief FX ,I went on line and found about KORU Nutrition and I brought a 3 pac when I received the relief fix I applied the ointment after 2 days I had relief from pain .I now I don’t any pain killers .I am soon to reorder my next 3pac I would recommend the now called KORU RELIEF
Relief Fx
I have been struggling with painful knees for sometime and nothing seemed to work until I found the Peter Williams advert on my smartphone about Koru Relief Fx for several weeks now and it has made a big difference.I now can move about more freely and with much less pain. I most certainly will keep on using this product. Customer service is excellent.
Relief Fx
I LOVE this relief cream! I incorporate it when giving therapeutic massages on those tight contracted areas on all my clients. Great results immediately! After a busy day my achy tired feet have healed so quickly with the application at the end of the day. I have also noticed I sleep so well too! After sharing it with my family and many friends I am receiving positive feedback from them all! Definitely the best topical cream I’ve ever used.
Relief Fx
What can I say? I automatically keep ordering because it is my drug free "go-to-first" pain relief product and hence I always have a supply handy for when needed. I always take it with me whenever I leave the house too and especially when I have the grandchildren with me.
Relief Fx
Apart from the benefits to my joint pain I have found that putting a small amount on mosquito bites immediately takes away the itch and reduces the swelling. Excellent product.
Relief Fx
I have been using Relief Fix for a couple of years now. It has made my physical life so much easier. I injured my knee 7 years ago, apparently not bad enough to operate on, but difficult to walk on and painful enough to be swallowing endless ibuprofen. However, since I started using Relief Fix, the pain has almost become pain free and swelling is minimal. I highly recommend it and giving some to my partner for Xmas.
Relief Fx
I bought this for my dad who suffers from all kinds of joint pain in all areas of his body. This has been the only instant relief product we have ever tried. I love it! Along with other Koru products. Definitely recommend
Relief Fx
Relief FX worked almost immediately allowing me to have some of the best nights sleeping I have had in ages. I fully recommend it for quick relief of joint pain, have used many other products but this is by far the best.
Relief Fx
Hi Molly I am delighted with your Relief FX cream. It has helped me with gout pain in my feet and I thank my friend who recommended I use your product for pain relief. I shall be using this ongoing and have also referred to another friend to use it. Many thanks, Tom Dunlop
Relief Fx
I am nearly 88yrs I have Ostio in lots of my joints but try tp keep as active as possible your cream has helped a lot for myself and my parter so I will keep using it thanking you Shirley Roper
Relief Fx
Photo is of Christmas baubles that I am putting stickers of our Village onto. Without RELIEF Fx this was impossible, but now my hands and fingers are so much more flexible. I gave a bottle to my neighbour, and pain in her hip/knee is now so much better she is back to going for walks again.
Relief Fx
The Relief Fix is my "go to solution to the osteoarthritis in my shoulders, arms and neck. I am a keen gardener and find I overdo it at times. Reaching for Relief Fix and resting a while means I can do more the next day be it walking, housework or being with my "grand puppies"
Relief Fx
Relief fx has been great for achy, inflamed joints providing immediate relief using the tiniest amount. It has also been really beneficial for bruising after a fall early this year. Within days the bruise was healing, and when applied after another nasty bump it cleared the bruise up in days. The packaging is brilliant, super easy and non messy to use and you can easily regulate the amount that comes out of the bottle. Ordering is seamless and easy as well, and the contact from Koru Nutrition ...
Relief Fx
Had crippling pain in both knees and shoulder. Started using this ointment after a friend recommended it. I was very sceptical, but decided to try it anyway having nothing to lose. This was only few weeks ago and already I am finding moving around is easier. I have all but given up using my walking cane, except for long distances. The stuff feels lovely and cool as it is applied, and quickly takes the pain away. Much of the inflammation of the joints has become less.

Reviews relief fx

What is Relief FX?

Relief FX is a natural supplement that is sold and marketed as a quick remedy for pain. According to the producers, it offers instant relief to pain when correctly used.

According to the manufacturer, this product is made in such a way that it relieves joint discomfort in the knee area, neck region, shoulders, and even down to the toes.

For this reason, the producers recommend it to people who are suffering from arthritis and related ailments, At the same time, it should not be used to replace the prescription medicines. The main work is to promote joint mobility by ensuring the joints are well-nourished and lubricated.

What is Relief FX and Company Behind Relief FX?

According to the producers, it is a natural pain remedy that is used to fight pain. The producers claim that this product is quickly absorbed into the system to give instant relief to aching joints.

Relief FX

They have described it as the fastest working pain relief in the market. This product is produced and marketed worldwide by People’s chemist. The company has six other supplements that they sell through third-party sites

What are the Ingredients Used in Relief FX?

The most active ingredient are;

  • Salix Alba
  • ZingiberOfficinale
  • Gelatin

How Relief FX Works?

Most pain killers used today are known to cause addictive tendencies or contain aspirin which doesn’t work well for some people. It uses the more Salix Alba to address the core source of pain. A study has been published in the Phytother Res. 2015 on the efficacy and safety of white willow bark (salix alba) extracts.

What are the Pros of Relief FX?

  • May offer instant relief to pain
  • Could relieve joint discomfort
  • Might promote joint mobility and flexibility
  • May lubricate joints

What are the Cons of Relief FX?

  • Unfortunately, it does not come with a money back guarantee or trial samples. Once you buy it, you cannot return it.

Relief FX Dosage

The recommended dosage is based on the weight of the individual. At the same time, the producers say that it is safe to use up to four tablets a day. The recommended dosage is three tablets with meals and lots of water.

Ideally, use one pill in the morning, with lunch and the other one with supper. If you wish to take four pills, take a pill every six hours. You can open the capsules and mix the contents with water if you want to get quick absorption.


As a joint care supplement, this product is below average. As a painkiller, this product is perhaps a little bit better than aspirin. It would work as a viable alternative to aspirin. Buyers should be cautious while using this product since the producers have not given us the clinical trial results. We have reviewed similar products such as Relief Factor and Arthrozene that are more reputable than Relief FX.

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