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19 Pokemon Who Could Beat Mewtwo In A Battle

Mewtwo is typically considered to be one of the most powerful creatures in the Pokemoncanon universe. And, though that is a truly bold statement, it is also a factual one. Very few creatures are powerful enough to go toe-to-toe with Mewtwo and very few are dim-witted enough to try it.

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Mewtwo is an incredibly powerful Pokemon that was genetically engineered to be a fighting machine. This makes it an all-around tank that cannot easily be taken down. However, there are a few creatures that can hold their own against Mewtwo. Though they might not be able to defeat Mewtwo outright, they will still provide enough of a challenge to keep things interesting and make it a rather equal match.

Updated on September 27, 2021 by Adriano Valente: Aside from having one of the most memorable designs of any Pokemon in the franchise, Mewtwo stands as one of the most powerful pocket companions trainers can get their hands on. The genetically modified Psychic-type once stood as the franchise’s undisputed powerhouse but has since been surpassed by various legendary, mythical, and everyday Pokemon. Despite this, there’s still a pretty short list of Pokemon that can beat Mewtwo out there. These incredibly powerful Pokemon stand the best chance of getting the job done.

19 Gengar

Gengar might not be as rare or powerful as a legendary Pokemon, but it can certainly put up a good fight against Mewtwo. These two Gen 1 powerhouses have remained some of the strongest of their type since first being introduced, receiving various forms and tweaks along the way.

Type weaknesses affect both Pokemon negatively here, putting them on a level playing field. Though Mewtwo gets the slight edge in Speed, Gengar has a versatile learnset that could prove to be the deciding force in a confrontation between the two.

18 Deoxys

This would be a battle between two Psychic-type heavyweights. Both Deoxys and Mewtwo bring a lot to the table, but Deoxys has the Gen 1 icon outmatched in its versatility.

Its four different forms let it capitalize on different stats, giving it the ability to gauge the battle and adjust when necessary. Its regenerative abilities provide it with a massive advantage that even Pokemon as strong as Mewtwo would have a tough time dealing with.

17 Eternatus

One of the newest Pokemon to be introduced to the franchise, Eternatus stands as an intimidating foe for any challenger. The Poison/Dragon-type outsizes Mewtwo quite a bit, ensuring an uphill battle for the Gen 1 Psychic-type.

Eternamax Eternatus is even bigger, completely overshadowing Mewtwo. Its signature move, Eternabeam, is an incredibly powerful attack that even Mewtwo would have trouble defending against. Though it might be an interesting match-up, Mewtwo could very well be outmatched.

16 Jirachi

It might not look the part, but Jirachi makes for a formidable foe in battle. The mythical Psychic/Steel-type has a peculiar ability that makes it difficult for any Pokemon to plan for during a fight.

With its wish-making ability, Jirachi is a true wild card that boasts a potentially game-changing power. It fares well against Psychic-types, which should give it a decent chance at besting Mewtwo.

15 Aegislash

Aegislash’s Blade and Shield Forme’s give it a noticeable edge in a fight, allowing the Steel/Ghost-type Pokemon to switch between a strong offense and iron-clad defense depending on the situation.

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Mewtwo’s status as a legendary might cause some to overestimate its ability in battle. While it’s certainly not as rare as Mewtwo, Aegislash has all the tools and abilities necessary to overpower the standout Psychic-type.

14 Yveltal/Xerneas

Mewtwo has tons of potential in its stats and movepool. However, in terms of what can match it, bulkier Pokemon that resist its variety of STAB attacks give it a run for its money. The best for this are bulky psychic-types and bulky fairy-types. Dark-types can also negate a lot of what Mewtwo can do offensively. Two Pokemon that fulfill all of these requirements are Yveltal and Xerneas, the box legendaries from Gen 6.

Both of these legendary Pokemon pack high offensive stats and HP, allowing them to bust through Mewtwo's sizable bulk. Moreover, they can each check Mewtwos that don't come equipped to handle them. Yveltal, although it needs to be wary of Ice Beam, can easily dispatch it with powerful dark-type attacks. Xerneas can easily check Mewtwo with its sizable bulk and even setup to become even more powerful. These would easily dispatch Mewtwo.

13 Aegislash

The blade, the myth, the legend that is Aegislash is another Pokemon that can match Mewtwo. Many ghost-types create problems for Mewtwo, as they exploit one of its biggest weaknesses. In some cases, Aegislash can completely wall out Mewtwo that don't have Fire Blast, Shadow Ball, or Earthquake. Shield-form Aegislash can take a ton of powerful hits even from this legendary beast.

Moreover, Aegislash's sword form can demolish Mewtwo with ease. Powerful priority moves like Shadow Sneak give Aegislash the ability to deal serious damage, and it boasts other powerful attacks to fill in the rest of its weaknesses. With excellent offense and defense, Aegislash is the perfect weapon to fight a godlike entity like Mewtwo. It earned its title of "Smogon Sword" for a good reason, after all.

12 Mega Sableye

Mega Evolutions, although they currently lay dormant in Sword and Shield, are a serious threat in many situations. Mega-Gengar, for example, could make quick work of Mewtwo without a second thought. However, sometimes the best offense is a good defense, and a good defense can lead to annoying your opponent into submission. Few Pokemon are as capable of doing that as Mega Sableye.

Sableye in its regular form isn't much to look at. Its Mega Evolution allows it to disarm status moves with Magic Bounce, then proceed to burn and Knock-Off the competition. Mewtwo in any of its forms can hardly dent this brilliant gem Pokemon, and its typing walls all of Mewtwo's potential stab attacks completely. If there was ever a Pokemon to make Mewtwo useless, Mega Sableye is the right option.

11 Alolan Muk

Mega Evolutions and obviously powerful regular Pokemon are obviously going to keep Mewtwo in check, that much is certain. So, how about an under-used Pokemon, brought from the trenches specifically to check and threaten legendary psychic types? Enter Alolan-Muk: a serious competitive threat. This multi-colored sludge, despite its weaknesses, has the right dark typing and moveset to keep many powerful legendaries in check.

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Alolan Muk's biggest boon is its ability to use Pursuit and trap Mewtwo in battle. If another Pokemon can weaken Mewtwo, Alolan Muk will always be able to finish the job. Of course, in Sword and Shield, Pokemon aren't legally allowed to use Pursuit as a technique. Does this make Alolan-Muk useless? Absolutely not, since it still has solid bulk and typing to survive an attack and retaliate with force. Mewtwo should be afraid of this sludge, despite its sweet smell.

10 Klefki

Legendaries can challenge Mewtwo. Gigantamax and Mega Evolutions can obviously challenge Mewtwo as well. Even a couple of regular Pokemon that have promise in high levels of play can take down Mewtwo. But, like Mega Sableye, how about testing Mewtwo's patience with one of the most obnoxious and bulky fairy types in the game? That's right, Klefki is the real secret to Mewtwo's destruction.

Klefki's ability, Prankster, always gives it priority with status moves. This allows it to paralyze Mewtwo for free, giving it room to set up hazards, confusion, or even attempt to fight Mewtwo head-on with Foul Play. Sure, if Mewtwo can execute a move to actually hit Klefki, it might not survive, but it has to be able to move first. With enough luck, they can definitely take down a Pokemon considered one of the most powerful in the Pokemon world.

9 Mew

There's certainly an argument to be made that the mythical Pokemon Mew can take down Mewtwo. Mewtwo is a simple clone of Mew. Mew holds the DNA of every Pokemon, and can learn every single move in existence. This is something that its clone cannot do.

Mew is the basis for Mewtwo's entire existence. Red and Blue even hints that Mew gave birth to Mewtwo. If there's anyone who can take down Mewtwo, who better to do it than its genderless parent? It only makes sense.

8 Anything That Is Dynamaxed Or Gigantimaxed

If we assume that the Mewtwo we are fighting isn't Dynamaxed or Gigantimaxed during the fight, then it can be assumed that any creature fighting it that is enlarged can take it down. They really only have to step on it to take it out.

Now, if Mewtwo is also Dynamaxed, then we have a much more even fight. It's alright though, we'll send all seven forms of Charizard out to fight it together. They'll overwhelm it numerically, it won't stand a chance.

7 Mega Mewtwo X And Y

Another easy contender to take down Mewtwo is Mega Mewtwo X or Y. Both of them are simply bigger and better versions of the original. When it gets into the fight, you're probably going to want to stick with Mega Mewtwo Y. Mega Mewtwo X is has a secondary fighting type, so it will be easier for base Mewtwo to take down.

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Mega Mewtwo Y is the same pure psychic type as the original with higher base stats, so it really should be an easy win for the Mega Evolved creature.

6 Arceus

Want to take down an opponent? Send in a god. Arceus is literally the Pokemon that created the universe, so even putting him in a Pokeball is incredibly disrespectful. If you're going to, though, then he's a good one to use in a fight against Mewtwo.

He's got great stats, and can use a Ghost Plate to become super effective against Mewtwo. He would obviously be a tough fight for Mewtwo with any Plate, but using the Ghost plate will just make it a surefire win for Creator Arceus.

5 Celesteela

Another option that might be a good check for Mewtwo is Celesteela. Mewtwo can dish out some heavy hits, so you're going to need something that can defend itself against it. That's where Celesteela comes in. It is an incredibly bulky Pokemon, and can use that bulk to slowly whittle away at Mewtwo's health through the use of Toxic and Leech Seed.

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Celesteela can take hits with the best of them, it has a niche in the AG, the highest power-level tier that there is. It's a great option to take down Mewtwo.

4 Primal Groudon

Primal Groudon has the ability to dry up the entirety of the earth if it wants to, so odds are that it could probably take out Mewtwo pretty easily. Groudon can do things one of two ways. It can go all out with its sheer power to take down Mewtwo, or it can play the very, very long game.

Mewtwo isn't going to win if Primal Groudon dries up all the water in the world, now is he? If Mewtwo eventually whittles away due to a lack of water, then Primal Groudon will have done its job.

3 Primal Kyogre

Primal Kyogre has the ability to drown the entirety of the earth if it wants to, which we believe is truly an asset when going up against one of the most powerful creatures in the canon universe.

As with Groudon, Kyogre can play the long game and outlive Mewtwo if needed by manipulating the available elements. However, it is important to note that it is a rather powerful Pokemon in its own right and could, at the very least, provide a bit of a challenge for Mewtwo.

2 Necrozma

Necrozma has four different forms (about 20% as much as Charizard) that it can utilize to take out Mewtwo. It has its base form, the ultra form, and its fused variants with Solgaleo and Lunala. All of these forms are incredibly powerful, but Ultra Necrozma really takes the cake here.

Its base stats are absolutely out of this world and few other creatures can compare to them. This is probably one of the best options on this list to take down Mewtwo.

1 Giratina

Giratina is a massive powerhouse that can easily hold its own against Mewtwo. However, it is important to note that it does have a type advantage against Mewtwo. This means that Giratina could take down Mewtwo pretty easily in either of its different forms. When a Pokemon has an advantage over another Pokemon, it is a good idea for said Pokemon to use it to its maximum potential. And if a Pokemon has the ability to manipulate its opponent's weaknesses, it should do so with no hesitation.

If we truly want to tip the scale in Giratina's favour, we could give our Giratina the home-field advantage and have the battle take place in the Distortion World. Mewtwo won't know what hit it.

NEXT: The Strongest Non-Legendary Pokemon That Don't Evolve, Ranked


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SB Mewtwo for Giratina Raids

Background: I don't have any Salamence or Rayquaza (haven't got enough candy to evolve my first, and missed raids last winter). I only have 2 dragonite (evolved and powered both from scratch - missed dratini community day).

So, with the supreme counters out of the way, I move on to the good counters.

Shadow Ball Mewtwo is listed, with Psycho Cut.

Except in the article about Mewtwo's movesets, it specifies that Confusion is better than Psycho Cut unless Psychic is resisted (or there's a double weakness).

Giratina is single-weak to Ghost, and doesn't resist Psychic. Shouldn't that mean Confusion-Shadow Ball is the optimal Mewtwo moveset to take it on?

If not in general, surely in Windy weather (what I had today), Confusion is better than Psycho Cut? (Of course, the dragons would be best, but as I began, I only have two Dragonite and of course they lead my battle party).

Other options:
Level 36.5 and level 35.5 Dragonites
Level 40 SB Mewtwo
Level 34 SB Mewtwo
Level 40 SC/SB Gengar
Level 36 BCr Tyranitar (my current team, mostly wanting ordering)

Potential subs:
Level 40 Meteor Mash Metagross (should I use this in Snow?)

I have other stuff that may be usable (e.g. more shadow ball mewtwo) but don't have the stardust to power it up (down to 24k after powering up the Metagross and my Dragonites, among maxing my best pokemon to 40 after leveling up - ouch).

Asked by TTT2 years 11 months ago

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15 Pokémon Stronger Than Mewtwo (And 15 Strange Ones Who Aren’t)

The philosophy behind Mewtwo’s creation was to make the world’s strongest Pokémon. Little did the scientists know how powerful their creation would be. Mewtwo far surpassed their expectations and was unwilling to be controlled by any corrupt official. He destroyed the laboratory that built him before traveling on his own and going into hiding. Several times, however, Mewtwo has come out to cause strife in the real world.

Since Mewtwo is a clone of Mew, there seemed to be only one Pokémon that could match him at the time of his original creation. However, Game Freak has vastly expanded its universe since then to include more powerful Pokémon, Ultra Beasts, and deities that can stand toe-to-toe with the lab-created powerhouse.

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Despite the power of Mewtwo, there are other Pokémon who are much more powerful. We’re simply positing who would win in a one-on-one battle between Mewtwo and another 'Mon. Because of this, we’re exploring 15 Pokémon who are stronger than Mewtwo and 15 surprising ones who we think are weaker. It’s an important distinction to make that we aren’t selecting characters based on their stats and moves in the games. For the purposes of this list, we’ll be drawing from mostly the anime, as it’s a more realistic depiction of their powers that adheres to the rules of its universe.

Had we solely gone with the games, there’d be somewhere around three or four Pokémon that would be stronger than Mewtwo.

Updated on October 12th, 2021 by Quinn Levandoski: The Pokémon franchise has continued to come out with more games and memorable monsters. The eighth-generation releases, Pokémon Sword and Shield, have introduced players to frighteningly strong pocket monsters like Eternatus, the Galarian Bird Trio, Zacian/Zamazenta, Calyrex, and Dragapult. These newcomers come equipped with new techniques and battle strategies that make them unique challengers for Mewtwo's reputation as one of the most powerful Pokémon in existence. 

30 Stronger: Arceus


As no surprise to anyone, Arceus made the stronger side of this list. Being the god of Pokémon (who also created the universe), Arceus has an incredibly impressive power level. Arceus exels in combat by taking advantage of type weaknesses, resistances, and immunities. With the capability to switch his type on the go, Arceus would be able to land the bug, dark, and ghost-type attacks that Mewtwo is weak against. Mewtwo might be able to get one or two hits in, but Arceus' type changes would also mean that Mewtwo's attacks would always hit at low or zero damage.

29 Weaker: Deoxys


While a fight between Mewtwo and Deoxys would be fairly close, Mewtwo has been shown to be the victor in the manga. Despite Deoxys' ability to swap between four different forms on a whim, Mewtwo outmatches Deoxys with its sheer psychic power. Mewtwo’s attributes are more than capable enough to keep up with Deoxys’ form changes, meaning that this alien just doesn’t have the stuff to defeat Mewtwo. Deoxys tricks would, however, ensure that this flight goes down to the absolute wire.

28 Stronger: Mew



Mewtwo is a clone of Mew. While Mewtwo’s savagery and raw strength might give Mew a run for its money, this little legendary still manages to come out on top. During their battle in the first movie, Mew seemed to have fun the entire time they were fighting.

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This suggests that if Mew were going full force it wouldn’t be much of a competition. Furthermore, Mew has the DNA of all Pokémon inside its body, allowing it to transform into any other living creature.

27 Weaker: Solgaleo


Solgaleo has interesting typing as well as a powerful command over the sun. Despite essentially being a deity of the sun and possessing some psychic powers of its own, it wouldn’t be able to defeat Mewtwo in a fight. Perhaps the story would be different if Mewtwo only had its standard form, but Mewtwo has two Mega Evolutions that make it one of the strongest Pokémon in existence. As a result, its immense psychic powers would overwhelm Solgaleo’s, meaning that Mewtwo would inevitably become the victor.

26 Stronger: Rayquaza


The strongest legendary in Hoen is perhaps one of the strongest Pokémon in all continuity. Rayquaza was already a serious threat to the Pokémon world, capable of fighting off a Deoxys by itself and calming a war between Groudon and Kyogre. However, the introduction of a Mega Evolution has caused Rayquaza to become a force of nature capable of blasting through meteors with ease. There’s no limit to the power of Rayquaza now, and Mewtwo would easily lose a fight with it.

25 Weaker: Darkrai



Despite the fact that Darkrai would have a type advantage over Mewtwo, it wouldn’t beat Mewtwo in a battle. In the manga, there was someone who had been running away from Mewtwo for a time. However, we’re told that he had a Darkrai at his side, suggesting that the sleeping powers of a Darkrai wouldn’t be enough to take down Mewtwo. Furthermore, Mewtwo can learn Aura Sphere, which would deal a critical blow to Darkrai, having a weakness to fighting-type attacks.

24 Stronger: Ho-Oh


Ho-Oh is one of the most heavily worshiped Pokémon in the Johto Region, and its world-shattering potential makes it easy to see why. Not only does this gracious bird leave a beautiful trail wherever it flies, bringing luck to those who simply gaze upon it, but it can even revive those who were deceased. That’s all without mentioning its powers, as its Sacred Fire attack ensures that no one would be able to fight against it. Its power over mortality means that Mewtwo would be on the ropes before long.

23 Weaker: Alakazam


Alakazam is one of the strongest non-legendary Pokémon. Its psychic abilities surpass many other Pokémon. It also has the IQ of a supercomputer, meaning that it can process and reason beyond what any human would ever be capable of. Despite all of its feats and a Mega Evolution, though, Mewtwo’s psychic abilities surpass Alakazam’s. Even in Mewtwo’s standard form, the fight might last a little while, but we all know who would come out on top. Those spoons won’t save him now.

22 Stronger: Palkia


Palkia is a deity with command over space. He can warp reality and send people to other dimensions. His battle with Dialga was so intense that the two of them had to be sent to their own dimension so they wouldn’t harm the rest of the world in the process. Palkia’s powers as a dragon and its immense abilities mean that most wouldn’t be able to stand a chance against it. Darkrai tried to stop both Pokémon in one of the movies, but he was soon defeated by both. We’d imagine Mewtwo would find a similar fate.

21 Weaker: Zamazenta and Zacian



Zamazenta and Zacian are legendary figures in the history of the Galar region, and most people didn't even know about their existence until they reappeared to stop Eternatus. These dog-like protectors may become quite powerful in their Crowned Shield and Crowned Sword forms, but their skillsets are targeted at taking down giant Dynamax and Gigantamax Pokémon. While Zamazenta and Zacian have decent typing to take some attacks from Mewtwo, they don't have a great way to deal with his long-range blasts or elusive maneuvering.

20 Stronger: Dialga


Palkia and Dialga would probably both be able to beat Mewtwo on their own. Palkia with its control over space, and Dialga with its control over time. That feat alone would allow Dialga to mess with Mewtwo and manipulate its surroundings. Furthermore, if Mewtwo managed to get a single hit on Dialga, all it would have to do is reverse time to get the better of Mewtwo’s strategy. That’s all without mentioning just how hard Dialga hits each time it lands an attack.

19 Weaker: Articuno, Zapdos, Moltres


Articuno, Zapdos, and Moltres were the only other legendaries in the Kanto Region alongside Mewtwo and Mew. They were each quite powerful, controlling a specific element that made them each the best in their class. However, Pokémon Origins showed us that even the power of these legendaries didn’t stand a chance against Mewtwo. It was able to shove aside Red’s Articuno without so much as a second thought. With its strength, we’d wager that Mewtwo would be able to defeat all three at the same time.

18 Stronger: Tornadus, Thundurus, Landorus

Having control over the weather is more than enough to make a Pokémon extremely powerful. Mewtwo can manipulate the weather with his psychic abilities, but Tornadus, Thundurus, and Landorus have a true command over it. Couple that with their Dream Forms that make them each much more powerful, and these three have a real shot at defeating Mewtwo. In the games, they pose a serious threat, and we’d imagine a similar thing would happen in-universe. However, they’d probably all have to work together.

17 Weaker: Regigigas



When it comes to underwhelming Pokémon, Regigigas certainly makes the top of that list. Despite somehow being the golem who presides over Regirock, Regice, and Registeel, Regigigas isn’t all that powerful itself. Sure, it was suggested to have towed the continents in place by dragging them, but its lack of speed means that it would just be a big target to Mewtwo. Mewtwo would be able to maneuver around it and make short work of it before it even had a chance to react.

16 Stronger: Calyrex



Calyrex was once the king of the Galar region, and it's one of the few Pokémon capable of taking on Mewtwo in a fight. Calyrex' base form may be better designed for peace than combat, but this ruler has a few tools that let it become a formidable opponent. First, Calyrex has the ability to see the past, present, and future. This means that Calyrex would see any of Mewtwo's plans coming before he could strike. Additionally, this Pokémon can bond with the ice-type Glastrier or the ghost-type Spectrier.

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While with the former, the pair is capable of dropping the surrounding temperature below -500 degrees Fahrenheit. Spectrier allows Clayrex to bombard its area with life-force stealing spirit flames. Either of these would be too much for Mewtwo.

15 Weaker: Dragapult



Dragapult is a powerful dragon Pokémon that takes advantage of its high speed and offensive capabilities to overwhelm its opponents. This Pokémon's secondary ghost typing does give it an advantage, and, if it can land a strong ghost-type attack, it's likely to do some serious damage to Mewtwo. Its downfall, however, is that it has very weak defenses. Mewtwo is able to tank a few hits even if they're super effective, but a strong ghost or dark-type attack from Mewtwo will quickly end the fight for Dragapult.

14 Stronger: Kyogre And Groudon


Kyogre and Groudon each have power over sea and land respectively. In their standard forms, it’s likely that Mewtwo would’ve been able to defeat them considering speed isn’t one of their strengths. However, with the addition of their Primal Forms, we’re singing a different tune. These Pokémon have become much stronger now, with the ability to make it permanently dry or rainy to boost their attacks. Their power just gets a massive increase at this point that Mewtwo likely wouldn’t be able to handle.

13 Weaker: Aura Lucario


Lucario is a heroic Pokémon known to be able to sense and channel aura in combat. However, it was the Lucario present in Lucario and the Mystery of Mew that managed to be one of the strongest Lucario in existence. It used aura to fight and communicate with others. It could even fight the Regi trio. However, this Aura Warrior Lucario wouldn’t able to fight against Mewtwo, even if it were to eventually unlock its Mega Evolution (which it didn’t even have in the film). Mewtwo’s strength would surpass Lucario’s with ease.

12 Stronger: Necrozma


Necrozma is one of the strongest psychic-type Pokémon, and it has some interesting attacks that take advantage of light. It also managed to combine with both Solgaleo and Lunala to form some powerful Pokémon. That said, we don’t think that Necrozma has enough potential to go head-to-head with Mewtwo and come out victorious. Mewtwo would be able to deal with Necrozma’s unique attacks. The battle might last a while, but Mewtwo has defeated Pokémon that are much stronger than Necrozma. There’s no reason to think he would lose this fight.

11 Weaker: Entei, Raikou, And Suicune


Entei, Raikou, and Suicune are powerful Pokémon that have been helpful in a pinch, but none of them have the potential to face Mewtwo and live to tell the tale. They were regular Pokémon created by Ho-Oh, so their powers are limited as a result. They are stronger than most Pokémon, but impressive speed and elemental powers aren’t quite enough to bring down Mewtwo. All it would have to do is deflect those attacks and the match would be over quickly.

10 Stronger: Kyurem Black And White


Kyurem would probably lose a fight against Mewtwo in its standard form. However, once it was able to merge with either Reshiram or Zekrom, Kyurem gained a much better fighting chance. Its abilities combined with another massive dragon legendary mean that its sheer power would probably be enough to overthrow Mewtwo. Furthermore, Kyurem was never formally defeated by Keldeo in the movie, just calmed down enough. This means that Kyurem has added durability that Mewtwo likely couldn’t handle.

9 Weaker: Zekrom And Reshiram


Where Dialga and Palkia were deities over time and space, Zekrom and Reshiram seemed like a step backward in the power department. Sure, they could generate fire and lightning unlike any other Pokémon in the world, but that’s where their strengths ended.

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With no special attributes outside of that, Mewtwo would easily be able to find an opening and exploit it. We’d wager he could also redirect their attacks or simply guard against them at the very least. It wouldn’t be much of a challenge for him.

8 Stronger: Giratina


Giratina has the benefit of adaptability and type advantage over Mewtwo. Not only does it sport a dominant Ghost-typing, but it can also travel through the Distortion World at will and bring its opponents there for home-field advantage. All it would have to do is send Mewtwo to the Distortion World, and it likely wouldn’t stand a chance. Furthermore, Giratina’s elusive abilities and strong Ghost-type attacks would probably give it the edge it needed to defeat Mewtwo.

7 Weaker: Mesprit And Azelf


While Uxie didn’t make it to this side of the list, Mesprit and Azelf wouldn’t be all that potent against Mewtwo. Sure, they have their own special abilities that the people of the Sinnoh Region find useful, but they don’t have the strength or power that could cause them to hold their own in a battle against Mewtwo. They’re the size of Mew but without any of its strength. Even if the two of them were working together, we’d wager that Mewtwo would make short work of them.

6 Stronger: Eternatus



At first glance, Eternatus seems to be at a disadvantage against Mewtwo because of its typing. Dragon/Poison means that any psychic attacks are going to land particularly hard against this cosmic threat, but Eternatus has an ace up its sleeve the Mewtwo doesn't have an answer for.

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Mewtwo is likely to start the fight out strong against Eternatus, but, once it enters its Eternamax form, Mewtwo is unlikely to have any effective attacks or defenses for Eternatus' massive 328-foot body. Zacian and Zamazenta were only able to stop this form with their special dyna/giganta/eternamax abilities, but Mewtwo lacks an equally specialized tool.

5 Weaker: Heatran


Heatran is an extremely durable Pokémon who can take a lot of hits, but he has no special abilities outside of a solid typing and powerful Fire-type moves. While its Steel-type would be resistant to Mewtwo’s psychic attacks, all it would take is an Aura Sphere and Heatran would be down for the count. Heatran could retaliate with moves like Overheat, but Mewtwo would be more than prepared for those attacks just by moving the fire out of the way or conjuring a psychic barrier.

4 Stronger: Galarian Moltres



A standard Moltres would be quick work for Mewtwo, but the incredibly powerful Galarian version would be able to hold its own. Its advantage starts with its typing. As a dark and flying Pokémon, Galarian Moltres would have the type advantage in both attacking and defending. Additionally, this legendary bird gives off a dark aura so strong that most Pokémon aren't even capable of going near it. This effect would be extra strong against a psychic Pokémon like Mewtwo, so, if he had to get close, he would be incredibly uncomfortable before the fight even began.

3 Weaker: Celebi


Celebi does have the ability to travel through time, but it doesn’t have command over it like Dialga. Even if it traveled through time, Celebi would keep its wounds, and that wouldn’t allow it to win a fight against Mewtwo.

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Mewtwo’s abilities far exceed Celebi’s. If the two were forced to fight with no retreats, it wouldn’t be long before Mewtwo would come out on top. That’s also without counting the fact that Mewtwo can Mega Evolve, in which the battle would be over much faster.

2 Stronger: Uxie


Why is Uxie on the stronger side? Sure, if it was a measure of its strength compared to Mewtwo’s, there would be no contest. Mewtwo would win. However, Uxie has an ace in the hole. Anyone who looks into its eyes has their memories removed. All that would need to happen is for Uxie to open its eyes and look at Mewtwo. At that point, the Pokémon would lose its memory and be able to be calmed down or open for a massive attack from Uxie.

1 Weaker: Lugia



Mewtwo and Lugia are both psychic Pokémon, but Lugia has an edge in the fact that it can also control water. However, Mewtwo’s psychic powers seem to be greater and it also seems to be faster and stronger than Lugia overall. The fight would probably last a while, but not if Mewtwo Mega evolved. Once it accessed one of its Mega Evolutions, the fight would be over in a matter of minutes. Lugia doesn’t have any special command over life and demise like Ho-Oh, which means it would probably lose in the end.

NEXT: 10 Legendary Pokémon With The Best Lore


NextEvery Unova Legendary & Mythical Pokémon, Ranked By Strength

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