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The 6 Best Insulin Cooling Cases Available In 2021

We need insulin to live, simple. 

So, it’s very important to ensure that we keep our insulin safe in everyday life. 

In certain circumstances, we can put our insulin at risk of dying; particularly when flying with diabetes supplies.

But thankfully there are ways to counteract this by using insulin cooling cases!

Below I’m going to take you through everything you need to know about insulin cooling cases and about keeping your insulin cold. 

What are the different options for keeping insulin cold? 

Thankfully we live in a world where innovation is high and that results in a lot of different options when it comes to keeping your insulin cold. 

Naturally, the best way to keep our insulin cold is via the fridge, but we don’t always have access to a fridge, especially if we are travelling, out shopping, camping, etc.

So when you don’t have access to a fridge, your next best option is an insulin cooling case! 

I’m going to take you through the best insulin cooling cases available on the market today, and show you what my favourite product is for keeping insulin cold. 

The best insulin cooling cases available today 

1. Frio - My #1 tool for keeping insulin cold

frio bags

Let’s start with the product I actually use.

I’ve been using Frio bags to keep my insulin cool for around 6 years, and I can honestly say, they haven’t failed me yet.  

Here is some information about the Frio insulin cooler to help explain what the product is, and what exactly it does. 

  • Frio bags are a unique product which is an evaporation cooling pouch that works by keeping your insulin cold when it’s not in the fridge. It’s simply activated by soaking it in cold water for a predetermined amount of time (it depends on the size of your Frio bag, but instructions are provided) 
  • It keeps your insulin between the temperature of 18-26°C (64.4-78.8°F) for 45 hours minimum, even in a constant environmental temperature of 37.8°C (100°F)
  • It can be reactivated for subsequent periods of 45 hours minimum for up to 28 days (however I personally have used them much longer than this)
  • They’re stylish and come in a range of designs and colours 
  • They actually work! 

Bottom line:This is my top recommendation for travelling through airport security with diabetes.

Check Price On Amazon

2. 4ALLFAMILY 72 Hour Insulin Cooler - Best insulin cooler for road trips

4allfamily72 insulin cooling product

This is another insulin cooling case option that's pretty unique!

The guys at 4AllFamily have sent me one to try out and it's an insulin cooling device that is in the form of a stainless steel cup.

The unique thing is that it looks like a coffee cup, so doesn't look "medical" which is something appreciate.

I hate things that look too medical.

The 4AllFamily 72 Insulin Cooler works in two ways:

1. Firstly there is the Biogel bottle, which you can refrigerate for 6-8 hours in advance then put it in your cooling case along with your insulin and cover it up!

2. If you've got access to electricity, (even the lighter in your car) you can put the insulin into your vacuum bottle and cover it with the black cooling cap. You then connect it power with the USB (have it on 30 minutes before you put your insulin in).

This combination of two ways to keep your insulin cool while on the go means it will pretty much keep you covered for all situations. Whether you're road tripping in a car or campervan, backpacking Asia, or even just on holiday!

I think that's really cool!


  • Can keep your insulin cool up to 72 hours
  • It's versatile and offers a variety of cooling methods in one product
  • It can be used with in-car 12V when adapted to a USB so a brilliant option for road trips!
  • Comes with a 1 year warranty


  • They only seem to have it in blue (which is nice, but maybe not for everyone)

Pro tip:Use the code THATDIABETICGIRL to get 10% off your purchase!

Check prices on their website

3. BreezyPacks

breezy packs

BreezyPacks are an awesome company that creates a really unique insulin cooling case.

They work by using a unique chemical absorbs energy when the temperature is hot outside and actively cooling the content of the case (PCM). When the temperature drops, the PCM regenerates by itself.

This basically means can simply pop your insulin inside and it will continuously be protected without a time limit. This is because the case recharges itself every night which I think is really cool!

Quick note, in order to recharge, they need to be at a cooler temperature (24°C/75°F or less) or, if you are short on time then you can put them in the fridge for 1-2 hours.

The product comes in two different forms, the BreezyBasic and BreezyPlus, which are basically the same thing, but differ in the amount of time they can protect your insulin in the heat.

The Basic can protect your insulin on a hot day for up to 6 hours, and the plus for 9!

You can fit 2 insulin pens in both, and probably around 3-4 vials (but I will confirm this when I use my product) 

What's also great is that the "plus" model can withstand even extreme climates, surviving entire days in the heat and temperatures of up to 46°C/115°F for shorter durations which is perfect if you're off on an adventure hike, or a day of city sightseeing.

I'll have a full review of the product soon which I'll link to when it's ready, but what I really like from first impressions, is the fact that there is no issues or complications or annoyance with "setting" it up, basically because it doesn't need any.

There's no need to drop it in cold water, like you have to with a Frio bag, or charge it, or even refrigerate it, and that's really cool.

Another great thing is they deliver worldwide which is useful!

I think this looks like a great placed product for day trips with diabetes, trips to the beach, camping trips, hiking adventures, or city breaks.

They're also creating a larger version coming out this fall, which will be able to hold even more insulin which will be a great solution for longer holiday trips AND backpacking adventures.

Buy your BreezyPack TODAY!

4. Poucho by Medicool - Great for keeping insulin cold during power outages 

This is another cooling wallet available from a different company known as Medicare.

This insulin cooling case appears to work in a similar way to Frio bags, however, I’ve not personally used one. 

Here are the important facts about Poucho: 

  • It’s easily activated by placing in cold water 
  • They can stay cool for up to 4 days 
  • There are two different colours and 6 different sizes to suit insulin pens and insulin vials 
  • Great for keeping insulin cold during power outages (which is something you often forget to consider!)

Check Price On Amazon

5. Eono by Amazon - great cooler for day trips

Eono is a new product developed by Amazon and it works in a similar way to the other insulin cooling products I’ve mentioned. However, it uses ice-packs rather than a smart in-built cooling system.

There are some advantages too it, including the fact it’s available on prime, and cheaper.

But let’s see how it compares in terms of ability:

  • The insulin carrying case has the ability to hold 4 ice cooling packs and a variety of insulin pens and vials
  • Before use you will need to put 2 or 4 cold gel and freezer to shape for 6-8 hours
  • The frozen ice pack could ensure the inside temperature at 2-8 degrees around 6-8 hours and keep it at the same condition for about 3-4days under 20 degrees
  • I would say this cool bag for insulin would be more suitable for day trips rather than long extended trips 

Check Price On Amazon

6. Lekesky - Another great option for shorter trips

This product is another insulin cooling case that makes use of ice packs. 

This means I would personally recommend Lekesky for shorter travel days and trips, and generally less stressful situations. Here are the facts: 

  • Keep insulin at 2-8℃ for 6-8 hours. Keep insulin at 25℃ for 48-72 hours
  • You need to freeze two cooling tablets in the freezer for 6-10 hours beforehand and the insulated panels help keep them cooler for longer periods
  • It comes with a unique and innovative Temperature Indicator which means the temperature of the insulin can be seen directly without using a thermometer
  • There is a 1 year warranty with the product for satisfaction 

Check Price On Amazon

BONUS: Medangel One Sensor - Fantastic tool for all bags 

the medangel one sensor

MedAngel is not a specific insulin cooling travel case, rather it’s an innovative piece of technology that allows you to track the temperature of your insulin in different situations. 

It can even make sure your insulin cooling case is working properly as you can pop the Medangel One Sensor into the case and monitor the temperature. 

The Medangel one sensor can also be placed in your fridge to ensure the temperature is correct and remove the risk of your insulin freezing. 

The sensor is synced up to an app on your phone via Bluetooth and it will give you alarms as to when your insulin is too warm and too cold. 

It’s a really great product to have when travelling, especially if you’re giving your insulin to a hotel fridge, or basically any fridge you don’t typically use. 

It’s also a worthwhile investment because you only need to replace the battery when it runs low. 

Check Price On Amazon

Or get 20% off when you purchase direct on the website (shipping restrictions apply) with the code:


Why do we need to keep insulin cold? 

keep insulin cold in heat

Insulin is a live product that keeps us alive, and in order for it to function well we need to keep it at a certain temperature.

If our insulin is exposed to extreme heat or cold, and fluctuates between these two temperatures, then it can destroy the insulin which will make it no longer suitable for use. 

Before you look at ways to keep your insulin cold, you actually need to consider whether it needs to be kept “cold”. 

What I mean by this is that if you’re taking your insulin away for a day and you aren’t expecting any crazy temperatures, then your insulin will be completely fine in your diabetic supply bag or purse, whichever you use, rather than an insulin cool pouch. 

But, if you’re visiting somewhere very cold, or warm, then it’s best to take extra precautions with an insulin cooling case to help ensure your insulin stays safe. 

Insulin can react adversely in cold temperatures. It can easily freeze when exposed to temperatures that it isn’t suitable for. 

I once put my insulin in a hotel fridge (or what they told me was a fridge) and it froze my insulin, solid. You cannot use it after it defrosts.

The insulin is dead and needs to be disposed of. 

Insulin can also react in warm temperatures. The heat can cause insulin to go cloudy or form clumps, and these are both indications that your insulin has died from exposure to the heat and it should again be disposed of. 

What temperature should insulin be unopened? 

For unopened insulin, which is still in the box, and hasn’t been used yet, the ideal place for your insulin is in the refrigerator at a temperature of around 2-8 degrees C [ 36-46° F]. If refrigeration is not possible, it can be kept at room temperature [15-25 degrees C] for 28 days. 

What temperature should insulin be after opening? 

insulin cooling wallets

For insulin that’s already been opened and that you are currently using the ideal temperature is 56°F and 80°F (13-26 degrees C).

And the insulin cooling cases we will discuss below will help you ensure your insulin stays at this temperature range. 

Other things to do note about insulin temperatures 

Insulin is supposed to have a 28 day expiration date, for in-use insulin. However, I honestly do believe this is just a guideline. 

Because I travel around the world with the same bottles of insulin for up to 4 months at a time, and my insulin has never, ever expired.

So, I would simply use your insulin and if you find your blood sugars aren’t in range, or you don’t feel like it’s working well, then you will know it has expired. 

It’s also recommended that in-use insulin should be kept at room temperature, and NOT in the fridge, but again, I keep my in-use insulin in the fridge and have yet to have any problems. 

This is a statement from the insulin company I currently use: 

Eli Lilly – Manufacturers of synthetic insulin's – ‘human’ and analogues.

"Our Humulin range has regulatory approval for in-use out of the fridge for 28 days. We have also performed our own in-house studies, however these were also completed after 28 days. Therefore, we do not have any data on in-use of Humulin vials after 28 days and thus, although we have no information to suggest that there is any problem with in-use vials stored in the fridge after 28 days, without data to support this we currently can only recommend in-use for 28 days."

Remember that insulin has an expiry date which is different from the 28 day use date.

Don’t use expired insulin. 

Some insulin's last longer than others, you should check with your doctor, or the insulin manufacturer themselves to find out how long your insulin is supposed to last. 

Choosing the best insulin cooling case for you

As I mentioned above, the only product I’ve used consistently is the Frio insulin cooling case and I also use the Medangel One Sensor, which has proved useful when I’ve been travelling. 

It’s saved my insulin a few times now which is great! 

So if I had to choose one product out of them all to choose, then it would naturally be a Frio bag! But that’s not to say that I won’t try other products in the future, but for now, the Frio bags have never let me down, so I don’t need to change products just yet. 

Before I found these products, I used to simply find a picnic bag and put some ice blocks inside them. 

I did this when I took a trip around South America, and it was honestly the most awkward and worst thing I could have done. 

I had to carry a bulky bag with me, which was unnecessary, and every day I had to keep re-cooling these massive ice blocks.

Thankfully, when I did some proper research, I found these great products instead. And now that there is lots of choice on the market, you’ll definitely be able to find something to suit your insulin cooling needs and if you're looking for a diabetic friendly gift, these insulin cooling cases are always a good choice!

Check Price On frio bags

So there you have it! 

My guide to the best insulin cooling cases available on the market today to help keep your insulin cool.

If you’ve got any other products to recommend, then definitely pop them below so we can recommend them to others too. 

Have you used any of these insulin cooling cases before? How did you find them? Let me know below! 

Check out some other useful posts:


8 Great Tools to Keep Insulin Cool

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When the hottest days of the year arrive, how do people with diabetes best keep their insulin cool so that it doesn’t go bad in the heat?

Whether you’re wearing an insulin pump filled with this life-sustaining medication or carrying around an insulin pen or glass vial, it’s critical to think about protecting insulin in the summer heat.

Severe storms and power outages can also present temperature concerns, making insulin coolers a critical tool to have on hand to ensure that this precious medication remains effective.

We’ve taken a close look at some of the most well-known insulin cooling products to help address this problem.

Frio cooling wallets

The Frio cooling wallets have been around since the late 1990s, and are arguably the most popular option. They are light, simple, compact, and easy to use. They are soft wallets that use evaporative water cooling to keep insulin in the sub-80 range for 48 hours, even when the outside temps are well above 100°F (38°C).

All you do is soak the cooling insert in water for 5 minutes before placing it back in the wallet cover, and it’s ready to use.

To reuse, you just soak the inner sleeve in water again and you’re good to go. Frios have the advantage of working in reverse, too, protecting insulin from getting too cold in freezing weather.

They come in a variety of sizes: from single wallets to carry one or two insulin pens, to larger, wider wallets that can hold multiple pens or glass vials and syringes. There’s also a wallet designed specifically to keep an insulin pump cool. This Frio size guide can help in the decision-making on which model is best for your needs. You can find these in various colors and some patterned designs, too.

Additionally, there are small Frio liners you can buy that can keep insulin pens, pumps, or supplies protected from water.

Frio cooling wallets range from $22 to $35 on the Frio website, or on Amazon.

Shop for Frio

Medicool cooling cases

Medicool cases have been around for quite a while as well, dating back to the 1980s. This company specializes in a wide range of insulated coolers with a molded insert that needs to be frozen, then re-frozen to be used again. It’s a step up from an ice bag, at least in terms of being less messy, but refreezing takes time.

They come in blue and black, generally rectangular shaped with an outside zipper. Some people like the hard cases because they are protective. But some of their larger Dia-Pak cases have a gel pack inside, which could be an issue if you travel and go through a TSA security check where a gel pack is flagged for inspection.

They also make smaller cooling pouches that are basically knockoffs of the Frio wallets, using the same water evaporation method to keep the insulin cool. These also come in various sizes and colors.

Depending on the case, you can also get a pocket or pouch inside to store other supplies like insulin syringes, a fingerstick glucose meter, and test strips.

Prices range from $20 to $30, sold at their website, Amazon, and various online diabetes supply sites.

Shop for Medicool

ChillMed cooling cases

Owned by the parent company Group Medical Supply that’s been making diabetes carrying cases since the mid-2000s, these ChillMed cases first launched in 2012.

The company makes a variety of diabetes carrying cases in different sizes and styles, including two styles with a built-in cooling element.

The ChillMed Go-To Medication Cooler is a small rectangular case available in red, blue, and gray. It comes with a re-freezable 3-ounce gel pack that offers up to 3 to 4 hours of cold time.

The ChillMed Micro Cooler is also a small rectangular case that comes in the same colors. But this one comes with a molded ice brick that fits two insulin vials or two pens, and offers up to 12 hours of cooling time.

Both bags have mesh pockets for syringes, medical wipes, and other small supplies

Prices range from about $20 to $22 for the bags, and about $9 for a replacement ice brick or gel pack, available at Walmart, Amazon and many diabetes supply sites on the web.

Shop for ChillMed

Thermos coolers for insulin

A newer trend in insulin temp control is the use of stainless thermos technology such as the Insulin Safe and its cousins, which can be found on Amazon, eBay, and Aliexpress/Alibaba.

One strong option, although pricey, is the 4AllFamily thermos cooler, which launched in 2019 and can store insulin safely for 72 hours. It actually uses three different cooling methods: You can switch the lids to go from a Biogel freeze pack to a USB-powered portable medicine fridge. Or you can use both simultaneously for maximum effect, keeping insulin at refrigerator temperature at or below 40°F (4°C) for up to 4 days.

With a large storage capacity (3.3-inch diameter and 900-milliliter total volume), this cooling case can fit up to 7 insulin pens, 42 Humulin vials, or 8 Novolog vials. At $140 a pop, it really is an investment for the whole family if needed.

On the budget end, there’s the much more affordable CaseMD product that is becoming popular in the diabetes community. Designed by physicians, it’s a compact vacuum-insulated container made of double wall stainless steel with vacuum insulation to guard against damaging heat or cold, humidity and UV light. It uses patented Thermashield technology to provide “ultimate temperature regulation to protect your sensitive medications.” These come in a regular and XL size designed to fit most injection pens, for $33 to $40.

Overall, insulin thermos products range anywhere from the low $30 range to upwards of $130 or more depending on the materials they’re made of. Find them on Amazon and a variety diabetes supply sites.

Shop for Thermos coolers

TempraMed Vivi caps

Unlike most of the above-mentioned products, TempraMed Vivi caps are specifically designed to keep a single insulin pen cool and protected.

What you do is use the Vivi cap to replace the cap on your disposable insulin pens, and the cap will keep your insulin at steady temps for years on end without electricity, water, battery charging, or refrigeration.

This magic is achieved using “cutting edge space grade insulation [that] is used in spacecraft, avionics, cryotherapy, and other demanding applications,” according to the manufacturer. “The heat absorbing activity is guaranteed to perform every day for years on end without requiring any user intervention. The monitoring electronics provides intuitive indication of the temperature of the medication.”

It starts working at around 84°F (29°C) and holds the insulin at 82°F (28°C). They also have a “coming soon” version for insulin vials, according to the TempraMed website, in August 2021.

This higher-tech product is on the pricier end at $95, available directly from Isreal-based TempraMed.

Shop for TempraMed Vivi caps

About insulin temperature

How hot is too hot? How long insulin can beat the heat?

The three major injectable insulin makers — Eli Lilly, Novo Nordisk, and Sanofi — told DiabetesMine that refrigeration temperatures between 36°F (2°C) and 46°F (8°C) are maintained for insulin products during the manufacturing process, and that remains the recommended range.

Read our in-depth coverage on insulin in the summer heat here.

Why are ice packs a bad idea?

Ice packs were the traditional solution. But while ice packs are great for post-surgical swelling, they’re not effective in keeping insulin cool. The ice melts quickly, they’re messy, and they actually keep insulin cooler than it needs to be, at least for insulin you’ve already opened and are using.

Also, it’s important that the ice not have direct contact with the insulin glass vial or the plastic insulin pen, as it could freeze the insulin, which also renders it ineffective immediately. For this reason, the insulin makers warn strongly against putting insulin in the freezer, or directly adjacent to the refrigerator cooling element.

Bottom line

Insulin itself is a pricey and life-sustaining liquid that needs protection, especially during the hotter months of the year and in case of disasters like a stronger storm or longer-term power outages. So, it’s a really good idea to investing in a trustworthy insulin cooling case — ideally one that doesn’t require melting ice or regular recharging. Fortunately, you have an array of styles, colors, sizes and cooling methods to choose from.

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Top 10 Best Insulin Carrying Cases 2020

Top 10 Best Insulin Carrying Cases 2020

1. Insulin Cooler Travel case, Organizer Medical case with ice Pack – Kits Medical Cooler Epipen Portable and Reusable Grey (2 Insulin Pen)

2. Apollo Walker Insulin Cooler Travel Case Diabetic Medication Cooler with 2 Ice Packs and Insulation Liner(Gray)

3. ChillMED Micro Cooler Bag – Diabetic Insulin Vial Carrying Case Travel Pack with Re-Freezable Ice Pack – Up to 12 Hours of Cool Time | for Insulin and Other Medication (Black)

4. SHBC Insulin Cooler Travel Case for Diabetic Organize Medication Insulated Cooling Bag with 2 Ice Packs Black

5. SHBC Compact Insulin Cooler Travel case for Diabetics Carrying On, Workin… New

6. Insulin Cooler Case Medication Diabetic Cooling Carrying Travel Pouch w/ Ice Pad

7. Insulin Cooler Case Diabetic Medicine Insulated Cooling Carry Bag with Ice Pack

8. Medicine Cooler Pouch Diabetic Insulin Travel Cooling Carrying Case w/ Ice Pack

9. Diabetic Bag Carrying Case Medical Travel Cooler Bag for Insulin Supply Kits

10. Diabetic Carry Case Medicine Cooling Pouch Pen Ice Bag Travel Insulin Cooler USA

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Top 5 Best Insulin Coolers 2018

5 Best Insulin Cooler Kits for Traveling Diabetics (Review 2021)

Traveling is an essential and a need, but as a diabetic, it's not always that simple. How do I keep my insulin cool? Can I fly without taking precautions? I'll share my personal experience as I traveled for 1 year abroad in Australia and review the top 5 traveling kits to keep insulin cool for diabetics. 

In this Diabetic & Me article you will learn about:

  • What is the importance of insulin?
  • How to keep insulin cold?
  • The precautions related to insulin and flying
  • What to pack while traveling as a diabetic?
  • What is the best insulin cooler travel case for diabetics?

Traveling As a Diabetic

It's a famous saying; "The world is a book, and those who do nottravel read only a page." (Saint Augustine)

But when you have diabetes you always hesitate to travel because you feel limited due to your diet, your medication, and possibly other health issues. This is normal. Before I met my current girlfriend, I never traveled for longer periods than a few weeks or longer distances than 4 hours of flying. After meeting my girlfriend, she traveled for 6 weeks by herself to Thailand (from Belgium), she convinced me to travel with her to Australia for 1 full year. We also traveled for a month in Sri Lanka and 3 weeks in Bali. It took a lot of courage and preparation but eventually, I did it. I'll share in this article a few of the things I took into consideration.

Instead of avoiding traveling you must take precautions and prepare yourself for any situation. In the end, you'll grab a ticket to your favorite destination!

What Is Insulin and Its Importance?

Insulin is a hormone produced by the pancreas. When you eat something, insulin gets the sugar from carbohydrates in your food. This way your body gets the energy it needs or stores energy for later. It regulates your blood sugar levels, makes sure it doesn't go too high (hyperglycemia) or too low (hypoglycemia). Without a working pancreas, your body starts using fat to produce energy but also produces keto acids. When these keto acid levels are too high you can get into diabetic ketoacidosis.

Insulin is an essential medication for people with diabetes type 1. If you travel and have diabetes it's important you always bring insulin with you. People with type 1 diabetes and some with type 2 diabetes always need insulin to maintain their sugar levels. Insulin is a temperature-sensitive medication and needs a cold environment to be stored. Insulin cooling is an important factor while traveling.

Treatments With Insulin

The method of taking insulin is called insulin delivery. There are many ways you can use insulin:

  • Syringe
  • Jet injector
  • Insulin pen
  • Insulin pump

Precautions Related to Insulin

A crucial point of bringing insulin with you or storing it is that it always needs to be kept in a cool or cold environment. Generally, while traveling or flying you don't have any electricity. So how to keep insulin cold without electricity can be a significant issue. Here are some precautions you should take into consideration when traveling and keeping insulin cool.

  • When exposing your insulin to extremely high or low temperatures it can change its chemical composition. This can cause insulin to not behave as it should and not control your blood sugar.
  • If you are traveling with, then always carry your doctor's prescriptions with you. Also, pack a signed document from your doctor that clearly states that you can travel with all of your medication. 
  • Your equipment and medication can behave abnormally during flights. Always read the user manual to avoid any unfortunate mishappenings.
  • Pack your insulin separately. If your insulin travel bag provides no extra compartment, then take a wet cloth and wrap it around your ice pack. Direct contact of a very cold surface with your insulin can freeze and damage your insulin.
  • If you want to keep insulin cold without electricity while traveling you can use  many of the insulin travel cases available.

The 5 Best Insulin Cooler Kits for Diabetics

Insulin, a temperature-sensitive medication, is the only solution for many diabetics. Traveling is a part of life that can't be avoided, so there is only a single solution left. Carry your diabetic medication while traveling and keep your insulin safe and cool.

If you are looking for the best insulin pen travel cooler, look no further, this is the best you could get your hands on. This insulin cooler uses 3 insulin cooling methods and keeps your insulin cool and safe for up to 72 hours. It can fulfill all your traveling needs.

The uniqueness of this cooler is that by changing the lids you can easily transform the bottle from a regular medication cooler into a mini-fridge. The USB function alone can maintain a constant temperature of around 27°F (15°C) lower than the outside temperature. If you use an ice pack as well simultaneously it will give an outstanding insulin cooling effect, such as keeping 35-46°F (2-8°C) cold for 48 hours and 36-46°F (2-26°C) for 72+ hours, when tested at an outside lab temperature of 104°F (40°C). Moreover, it is patented so you will never find the same quality in other insulin coolers.

After testing and using it myself this is worth it. Looking forward to doing some longer travels with it.

Read more about 4ALLFAMILY in the company review or read the insulin cooler review.

Key Features:

  • It offers 3 insulin cooling methods to suit your needs.
  • It is made up of rust-free and high-quality stainless steel which enhances its durability and keeps your insulin safe.
  • The best thing is that it can store up to 7 insulin pens. It might even fit two insulin pumps.
  • A universal USB 2.0 adapter is used to charge the cooler. You can charge it with a power bank as well.
  • An extended nylon belt is attached to the collar, giving you an extra grip.
  • You can charge it up with a solar panel or with your car battery easily.

Insulin cooling was never easier. This insulin cooling bag is the perfect pack for days when the temperature and humidity levels are high and your insulin needs to stay safe. The Breezy Packs Plus Insulin Cooler Bag will keep everything cool, so you don't need to worry about spoiling your medicine or running out. For people living in very muggy climates, this is a lifesaver!

It is made of quality material that lasts at least 9 hours at 38°C/100°F and full days at lower temperatures. Safe for use at up to 46°C/115°F for shorter durations. A unique feature on the "plus" model that will automatically replenish overnight without needing charging, minus all those pesky dead batteries with no way of getting rid of them while traveling.

Keep your insulin pens and insulin vials cooler than the outside temperature.

The FRIO insulin cooling bag gets a solid number 2. I used them myself when I took a flight from Belgium to Australia. It was a flight to Bangkok of 12 hours, a transit time of 14 hours, and the second flight from Bangkok to Sydney was 9 hours. These insulin cooling bags made it easy to keep my insulin cool during that time.

Taking ice packs is not always that convenient. If you're familiar with diabetes medications, then you know that without ice packs, it's impossible to remain your insulin cool for a more extended period.

FRIO is a leading brand in insulin travel cases and insulin cooling bags. Each package consists of two parts; one inner bag and one external bag to carry the internal bag with insulin and vials. When soaking the inner bag in the water you activate the insulin cooling bag. Water activation technology is a recent invention used by travel and insulin cooling cases.

Each time you soak your FRIO bag in water for 10 to 15 minutes and place your insulin inside, the insulin will remain cool for 2 days. The most important thing about the FRIO bags is a weight of 0.8 ounces with a vast capacity of placing four insulin pens and 5 to 6 vials efficiently.

A reusable product in this age of disposable things is an eco-friendly step. A variety of sizes is also available, so you can buy a FRIO bag that suits you. Keeping in mind people's choices, four colors; red, black, blue, and purple, are also available.

Carrying insulin with you is a bit risky, but if you have an insulin travel cooler, it will be much more helpful. This insulin cooler travel case can be a great deal for a diabetic.

Things you carry with you must look good too. This grey-colored insulin travel case looks slimmer but has much more space than any other insulin case.

Key Features:

  • Durable polyester gives it a much longer life and makes it more robust.
  • A particular insulating layer stitched inside to lock the insulin cooling is in the case and resist external heat.
  • Dual zippers are added to give it a premium look.
  • A much more compact size with a rigid frame avoids any damage to your insulin.
  • Two ice packs come with the package, which is a unique point.
  • An inside compartment separated with mesh fabric can be used to store the icepacks.
  • It's waterproof. This unique feature makes it more convenient for outdoor use.
  • A cashback warranty of 30 days can win anybody's confidence.
  • Dimensions of this insulin travel case are 7.9" x 3.5" x 1.6" with a weight of 6.4 ounces.

Rohkler comes with a suitable solution, an insulin cooler travel case for diabetic supplies. It's one of the best insulin pen travel coolers on the market and it comes with an ice pack.

The significant features which differentiate it from other insulin cases are.

Key Features:

  • It has plenty of separate compartments to carry all your diabetic supplies.
  • Four extra ice packs also come with its packaging.
  • Typical insulin travel cases have a thickness of 5.5mm. This travel cooler has a thickness of 6mm, which means it's more efficient than others.
  • The whole interior compartment is customizable. It gives you the flexibility to organize your supplies as you want.
  • It looks like a mini suitcase with a tough exterior. This makes it durable and your supplies are stored much safer for outdoor use.

It's one of the best portable insulin cooler travel cases you ever see.

The unusual feature of this bottle is that it can maintain a temperature of 2°C to 8°C for almost 28 hours. A proper way to use is to keep this bottle in a freezer for 6 to 8 hours and then leave it to cool down at room temperature for 5 to 10 minutes.

The performance of this insulin travel cooler bottle is ten times better than any regular freezer bag.

This most spacious insulin cooling kit can store up to two insulin pens with four vails.

Its stainless steel body makes it durable and rust-free. The downside is that if you want to travel for a longer period you are not able to carry much of your medication.

Four color steel variants are available Gray, Silver, Red, and Blue, providing you a good range of colors. It's TSA Approved and you have one year warranty with a refundable one-month warranty.

How Do I Keep My Insulin Cold While Traveling?

Always try to place your medication and snacks near to you — a place where you can easily reach it during flight. Sometimes you don't have time to ask something from a flight attendant if your sugar level starts dropping down rapidly. If you're using a pump for insulin delivery you must take advice from your medical personnel. Takeoff and landing are two critical points where the pressure in the cabin becomes unbalanced and can result in pump failure. I flew many times and had no issues.

If your flight is longer, then check your glucose levels after intervals. Your glucose meter with extra strips or your CGM must be with you all time.

What To Pack While Traveling

When I fly I always have some Sprite (sugar drink), extra medication for a week, and my insulin in my bag. If my luggage doesn't arrive I always have this bag with me and I have my equipment and medication with me.

When you're maintaining your schedule according to your medical conditions never skip your precautions and don't compromise your life for short-time fun. Long-term traveling with type 2 diabetes or type 1 diabetes is not an easy thing and certainly not something you should do without thinking.

As a diabetic, you must prepare yourself for traveling no matter if it's a more extended vacation or a one-day tour. Carrying with you a signed document from your doctor that clearly states that you can travel with all of your medication saves you from the hassle during airport securities. When I traveled to Bangkok, Thailand it was difficult to explain everything but the fact I had all my medication and signed documents and prescriptions with me made it OK for them.

Create a checklist before packing is a must-have. Below you can find an example of my packing list. I am using a FreeStyle Libre CGM and a MiniMed 640G insulin pump. I packed to travel one year.

  • Passport
  • Spare prescriptions + copies
  • Travel insurance papers
  • AA Batteries
  • Charging cables (Phone)
  • EHBO set
  • FRIO insulin cooling bags
  • 16 Freestyle Libre sensors 
  • 82 catheters for the pump
  • 100 syringes for the pump
  • 40 bottles of Humalog insulin
  • Extra Humalog for MDI if my pump would defect
  • Extra Toujeo insulin if everything fails
  • Wet wipes and alcohol swabs or wipes, if you're in a remote area

Me During My Travels Through Australia and Sri Lanka

Does Flying Affect Diabetes?

Traveling is all about planning. Flying with diabetes can be a bit more challenging than you think. Flying does not affect your diabetes in a direct way but it can have an effect on your blood sugar levels. From a proper diabetic meal to the unexpected stress during flight or in the airport waiting area, everything needs your care. Usually, business class and long domestic traveling airlines offer complimentary meals to their passengers. Some of them take special care of their passengers and provide meals with sugar-free or low-carb options. Before booking your flight, check these things first.

Take an in-depth look at which are the crowded places and what you should expect can make your travel a bit easier.

Precautions Before and During Flying

Some of the precautions I took and wished I took before flying.

  • When you're traveling in a different time zone, reschedule your insulin delivery time. This is a lifesaver. Especially when you are using an insulin pump.
  • Carry your doctor-recommended prescriptions of any equipment or medication you are taking.
  • Pack with care. Give everything a place so you don't need to start looking after stuff when you need it the most.
  • Every time you travel (far), never do this without travel insurance. You probably never need it but when you do you might not have it.
  • Always be conscious about your meals during the flight. They might contain more sugars or higher carbs.
  • Pack all your medical health care things apart from other essentials. A separate bag that you take on the plane with you is not a bad idea.

International Standards for Storing Insulin

If you want to store your insulin for a much more extended period, then you must follow international standards. The standard is that you have to store your insulin in a dry environment within a temperature range of 2°C to 8°C. The critical temperature on which your insulin starts decaying is 25°C. Never let your insulin hit this top line. The bottom line is to never freeze your insulin. It will stop working.

According to NHS Solent Trust,

  • Syringes related to the delivery method must be kept in a fridge
  • Pen-filled insulin cartridge packaging must not exceed 10ml
  • Only recommended 8mm or below 8mm syringes should be used
  • Shake your pre-loaded insulin 20 times back and forth if you're using cloudy insulin

More About Traveling With Insulin

Find out more about traveling with diabetes and diabetic-related travel products in the articles below.


No matter what type of diabetes you have, you just need to do a little bit of homework before traveling. Four to six weeks before traveling you need to plan your diet, insulin dosage, medical insurance plan & your doctor's authorization. A travel cooler to keep your medication cool is a must. If you're alone make sure you tell someone on the place or in your hotel that you are a diabetic. If you have been following the procedures mentioned above, then there is nothing to be worried about. Enjoy your traveling alone or with your loved ones.


Case insulin cool

1. BreezyPacks

breezy packs

What are BreezyPacks?

Looking for an easy breezy insulin travel case that keeps your insulin cool? Then look no further.

The BreezyPacks are cute, small cases that can hold temperature-sensitive medicine, i.e. your insulin!

They work by using a unique chemical that absorbs energy when the temperature is hot outside and actively cooling the content of the case (PCM). When the temperature drops, the PCM regenerates by itself.

What this means is you can simply pop your medicine inside and it will continuously be protected without a time limit. This is because the case recharges itself every night (pretty cool!)

They need to be at a cooler temperature to recharge (24°C/75°F or less) or, you can also pop them in a fridge for 1-2 hours to quicken the process)

The fact that you can keep reusing this product means that it's a worthwhile investment and means you'll get great value for money. Your insulin will be protected on all your future adventures.

I also love that its made with recycled and eco-friendly materials, a VERY important feature in todays world! 

There are currently 2 models on offer (with more in the pipeline).

The BreezyBasic and BreezyPlus.

The basic can protect your insulin in a hot day for 6 hours , and the plus for 9 hours.

**note this was tested at 38°C/100°F, away from direct sunlight**

Both of them fit about 2 insulin pens, and I'm not sure on insulin vials yet, but I'll let you know when I know!

The "plus" model can withstand even extreme climates, surviving entire days in the heat and temperatures of up to 46°C/115°F for shorter durations which is perfect if you're off on an adventure hike, or even taking a trip in the Amazon rainforest (this would have served me useful back on my Brazil backpacking trips!)

I'll have a full review of the product soon which I'll link to when it's ready, but what I REALLY love from first impressions, is the fact that there is no issues or complications or annoyance with "setting" it up, basically because it doesn't need any. You don't need to dip it in water (like a Frio bag), or charge it, or even refrigerate it, and that's really cool, especially for someone like myself who likes things to be easy, breezy....;) 

Another great thing is they deliver worldwide which is useful!

I think this looks like a great placed product for day trips with diabetes, trips to the beach, camping trips, hiking adventures, or city breaks.


  • Easy to pack size
  • Continuous use (recharges itself at night)
  • There is no faff, you don't need to dip in water, freeze, or do anything for it to work!
  • Recyclable materials and good for the environment
  • 3 year guarantee (that shows confidence!)


  • Holds a smaller amount of insulin (this is coming from someone who goes on VERY long trips, so I think for the average diabetic taking an average trip it would suffice!)-- I know they have a BreezyMega coming soon which will be perfect for longer trips.
  • If I find any cons when I test the product I'll pop them here
‍Buy your BreezyPack right here!

2. Fridge-To-Go

What is Fridge-to-go?

It’s an insulin travel case that basically promotes a unique range of cooler bags that help keep your contents cold for up to 8 hours.

They are described as durable, collapsible, easily stored, re-usable and environmentally friendly.

The front page recommends them for packed lunches etc, but I thought, wouldn’t it work for insulin for shorter duration's?? I did some digging.

They do have a ‘Medical wallet’ specifically designed for holding medication.

They do both a large one, which looks as though it could hold around three-four insulin pens, so around 5-6 insulin vials. The smaller bag seems as though it would hold around two insulin pens and around 4 vials.

The bags are advertised as a short-term solution to keeping your insulin cool, and I would agree with that.

The insulin travel cooler lasts up to 8 hours which is perfect if you’re heading out for the day in the sunshine, at the beach, or even take a long car journey.

As long as your travel duration doesn’t exceed the 8 hours, then this is a good product for those “in-between” moments of travelling.

If however, you are taking 12-hour bus journeys or your insulin won’t be in a fridge for a full 24 hours, then it’s probably best to consider an additional product for those times.

I haven’t tested this product first hand, so I cannot vouch for its effectiveness, but if you have then let us know in the comments what you thought.

Maybe I’ll get a chance to try it on my travels and let you guys know how it works.


  • Great insulin travel case for short-term journeys for up to 8 hours
  • Good for a beach day
  • Easy to use ( simply freeze the insulated pack in the freezer overnight for minimum 12 hours) and it’ll keep your insulin cool.
  • It’s light and easy to pop into a rucksack or day bag


  • Not a great variety of different sizes or styles
  • Not good for overnight insulin cooling needs or long-travel journeys such as a long-haul flight
  • Can’t hold long-term quantities of insulin for long trips away

These guys are an Australian company, but these products are available in the USA, Canada and further afield.

Fridge To Go insulin cooling bag

3. The 4ALLFAMILY 72 hour Insulin cooler travel


This insulin cooling case is actually pretty cool! The guys at 4AllFamily have sent me one to try out. This is basically an insulin cooling device that is in the form of a stainless steel cup.

What I actually love is that it looks like a coffee cup, so doesn't look "medical" which is something I always try to avoid when choosing insulin cooling cases.

It actually works in two ways: Firstly there is the Biogel bottle, which you can refrigerate for 6-8 hours in advance then pop it in your cooling case along with your insulin and cover it up! OR, when you have access to electricity, you can put the insulin into your vacuum

bottle and cover it with the black cooling cap. You then connect it power with the USB (have it on 30 minutes before you put your insulin in).

This combination of two ways to keep your insulin cool from one device means it's a perfect travel companion. You're able to keep your insulin cool when you don't have access to a fridge, THEN when you reach electricity, you can switch to the USB.

I think that's really cool! 


  • Can keep your insulin cool up to 72 hours
  • It's versatile and offers a variety of cooling methods in one product
  • It can be used with in-car 12V when adapted to a USB so a brilliant option for road trips! 
  • Comes with a 1 year warranty


  • They only seem to have it in blue (which is nice, but maybe not for everyone)
You can buy online here and get 10% off with DREAMBIGTRAVELFAR

Read this review here.

4. Medicool

The next insulin travel case I want to look at is Medicool.

Medicool actually is a website that houses a whole host of different insulin travel coolers and cases, so I’ll go through the ones I discovered on my searches and weigh up the pros and cons for traveling with type 1 diabetes.

Dia-pack: This is an insulin cooling case with a unique twist.

Not only is this insulin travel case fully insulated, but it comes with an electronic temperature display that reads the outside temperature! How cool is that? Pretty cool I thought. This product can keep your insulin cool for up to thirty hours, and it has the ability to carry needles, syringes and other medications you may require. It includes a re-freezable gel pack, meaning it can be reused, and a shoulder strap, which I guess is convenient if you want to hold it in your shoulder.


  • Keeps your insulin cool for up to thirty hours. This is good for flights, long car journeys, or even an overnight stay camping, at a hostel with no fridge etc. It’s also good for 24-hour bus journeys, but honestly, I ain’t going to recommend you even take one because they are so uncomfortable!
  • Comes in a range of different cases to suit different occasions, the elite, classic, deluxe and the day mate which is perfect for those day outs.  You can buy replacement gel packs to reuse the cooler


  • They don’t seem very “fashionable” and not a lot of different colours on offer. You have to pay for replacement gel packs which means extra expenses to reuse
Medicool Pen Plus Diabetes Cool Bag

5. Poucho

They are activated via water and are great for keeping insulin safe when it’s not being refrigerated.


  • It’s activated by water so pretty convenient when your travelling with diabetes
  • It can be re-used hundreds of times, which again is perfect for when you are on the road a lot
  • The cooler stays cool up to four days, which is good for city-breaks, camping trips etc
  • There are 6 different sizes to suit your insulin requirements.


  • There isn’t a lot of colour choice of product
  • 4 days isn’t as long as other products

But honestly, I think this is a pretty decent product, and perhaps I’ll get the chance to try them someday, but they are essentially the same as Frio bags, but Frio bags stay cooler for longer, which suits me better when I am travelling long-term, but these are a great choice if you are heading off on holiday!

Single Pen Poucho 2 1/4 x 6 1/2

Double Pen Poucho 3 1/4 x 7

Small Poucho 5 1/2 x 6

insulin travel case

6. The MediCool Insulin Protector

This is probably the least favourite of the insulin travel cases I’ve come across, not because I don’t think it’s useful, but I don’t think it’s a good choice for travelling with type 1 diabetes.

But, let's consider and look at the details.

The Medicool Insulin Protector Case can keep your insulin cool for up to 12 hours, so it’s definitely a good choice for a long road trip or flights or even a long day out at the beach. The problem is, it only holds up to two bottles of insulin, which really means, it’s not suitable for long-haul trips.

Two bottles of insulin would typically last me, around 20 days, give or take, which of course is fine for a 2 week holiday, the only problem is, that leaves me no room for spares, and it’s imperative that you take spares with you whilst travelling with insulin.

However, if you are on a short-term trip, then maybe this is the choice for you. It also comes with two cooler packs so you can refrigerate one whilst using the other. You can get it here.


  • Good for a short-term trip or day trip


  • You can’t carry more than 2 bottles of insulin
  • Doesn’t fit pre-filled insulin pens
  • Not a wide range of styles
  • Looks bulky and ‘medical’
  • Overpriced for what it is
Medicool insulin protector

7. iCool Prestige

This product keeps your insulin cool for 12, 24 or 36 hours, (depending on which version you buy), but it can be reactivated for another 24 hours, and so on so forth. 

The thing I really like about this product is that it has the space to organize around three weeks supply of your medication….which is a really great amount. Therefore, for example, if I am heading off on a trip to live in Austria for a month, (which I did), then it will keep my insulin cool until I arrive there and transfer it to a fridge, and it will have the amount of insulin I need!

However, it is an expensive choice coming in at 65 euro. But as far as insulin travel cases go, I’d say this doesn’t seem like a bad one.

They also offer a range of small cool bags for medication too, which means you can find something to suit you. But, it doesn’t have a wide range of colours and looks a little clinical. (I’m not sure if you have realised but I don’t like things looking clinical!)

Icool for insulin

8. Frio bags

Last, but by no means least, I’ll give a review of Frio. As you might well know, this is my product of choice and I have used it for 4 years now, (the same bags), and I have never had any insulin die. I think this reflects just how well they work. For me, they work even better than they actually recommend!

So, what are Frio Bags?

If you haven’t already checked out my other babblings about Frio, then you might not know that Frio bags are a device that keeps your insulin at the required temperature when you don’t have access to a fridge, so either flying, camping, hiking, etc.

The Pros

  • Frio bags keep your insulin cool and safe, the required temperature for in-use insulin is 18 to 26 degrees, and this is exactly the temperature that Frio bags aim for.
  • They look good. I don’t think Frio bags cool “clinical”, which is one of the main reasons that I like them. I don’t like to look clinical, I like to look fun, and their awesome range of colours mean my diabetes can stay cool in purple and pink tones.
  • They come in a range of sizes.
  • Small Double which will fit two pens
  • Large Wallet which will fit 10 insulin vials or around 6 pens. I fit in around 12 vials in my case.
  • Extra Large Wallet which will fit around 15-17 vials for me
  • Sometimes I need one Frio bag, sometimes I need two...and on a three-month trip, I need three! I like that you can get a full range of different sizes to suit your trip. (I also like that I can fit in more than they recommend! :P)
  • Frio wallets can be reused OVER AND OVER again! The Wallet can be reactivated and used for subsequent periods of 45 hours minimum for up to 28 days- however, I have used mine for over three months at one time and I have never encountered any issues.
  • They are so simple to use: you simply activate them with cold water- nothing fussy! They say they last up to 12 months or longer, depending on your usage, but I have had my oldest Frio bag for three years and it’s going strong.  
Insulin travel case

I personally think Frio is the most reasonably priced for the style, quality and use you get from them! 

Plus, you can shop around on Amazon, and other outlets to compare prices to find a cost that suits you- either way, you're still getting a Frio bag!

I’ve purchased one of mine direct of Frio, one off Amazon, and another I was given to review by Frio themselves (Thank you!) I used them before I got given one to review (it was their newest design), so that doesn’t make me biased BTW! :P

I really can’t give any major cons to the Frio bags, because it’s the thing I use every time I am travelling, so if I thought there were any major concerns I wouldn’t use it! They also have their newer Insulin Travel Case which has multiple compartments to hold all your Frio wallets, diabetic supplies and a sharps bin.

They are have a beautiful range of wallets that are fashionable and stunning! Check out mine here.

You can get an exclusive 20% off when you purchase the eBook or course.

BONUS: The MedAngel One

This isn't a insulin travel case, rather it's a sensor that helps you track whether your insulin is at the required level to stay alive. It's a really cool sensor you pop into your fridge, or beside your insulin, or inside your chosen insulin cooling wallet and it can test if you insulin is too cold, too warm, or just right!

This is a perfect device for travelling to destinations that are known for their heat or cold and great for if you are backpacking and using dodgy hostel fridges. It tracks your insulin via an app on your phone and right now you can get a generous 20% off a sensor when you purchase our eBook or course. The sensor battery lasts for nine months, and it can be replaced so can be used for as long as you need it!

I have completed a full review on this product here. If you would like to purchase one, you can do so below:


So there you have it, my guide to the best insulin travel cases I could find on the market in 2019. Comment below if you use any of the products above, OR if you know of any other insulin cooling cases that I can add to the list!

Happy Travels, and as always, Dream big, and travel far!

Cazzy xx

FRIO Insulin Cooling Case Demonstration


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